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Article

Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy

3 Jun 2010

Abstract excerpt

AIMS/HYPOTHESIS: We sought to establish the extent and basis for adaptive changes in beta cell numbers in human pregnancy. METHODS: Pancreas was obtained at autopsy from women who had died while pregnant (n = 18), post-partum (n = 6) or were not pregnant at or shortly before death (controls; n = 20). Pancreases were evaluated for fractional pancreatic beta cell area, islet size and islet fraction of beta cells,...

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PMID: 20523966
DOI: 10.1007/s00125-010-1809-6

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