Article
Pituitary volume in patients with bipolar disorder and their first-degree relatives.
Journal of affective disorders - 1 Aug 2010
Takahashi Tsutomu, Walterfang Mark, Wood Stephen J, Kempton Matthew J, Jogia Jigar, Lorenzetti Valentina, Soulsby Bridget, Suzuki Michio, Velakoulis Dennis, Pantelis Christos, Frangou Sophia
Abstract excerpt
BACKGROUND: Hypothalamic-pituitary-adrenal (HPA) axis dysregulation has been reported in bipolar disorder (BD), but previous magnetic resonance imaging (MRI) studies of pituitary gland volume in BD have yielded inconsistent findings. In addition, the contribution of genetic factors to the pituitary changes in BD remains largely unknown. METHOD: We used MRI to investigate the pituitary volume in 29 remitted...
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