Article
Amygdala and hippocampal volumes in relatives of patients with bipolar disorder: a high-risk study.
Canadian journal of psychiatry. Revue canadienne de psychiatrie - 1 Nov 2009
Hajek Tomas, Gunde Eva, Slaney Claire, Propper Lukas, MacQueen Glenda, Duffy Anne, Alda Martin
Abstract excerpt
OBJECTIVE: Bipolar disorders (BD) have a strong genetic underpinning, yet no biological vulnerability markers for BD have yet been identified. To test whether amygdala or hippocampal volumes represent an endophenotype for BD, we measured mesiotemporal volumes in young affected and unaffected relatives of patients with BD (high-risk design). METHOD: High-risk participants (aged 15 to 30 years) were recruited from...
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