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Article

Changes in glomerular mesangium in kidneys with congenital nephrotic syndrome of the Finnish type.

Pediatric nephrology (Berlin, Germany) - 1 May 2010

Kaukinen Anne, Kuusniemi Arvi-Matti, Helin Heikki, Jalanko Hannu

Abstract excerpt

Congenital nephrotic syndrome of the Finnish type (NPHS1, CNF) is an autosomal recessive disease caused by mutations in a major podocyte protein, nephrin. NPHS1 is associated with heavy proteinuria and the development of glomerular scarring. We studied the cellular and molecular changes affecting the glomerular mesangium in NPHS1 kidneys. Marked hyperplasia of mesangial cells (MC) was mainly responsible for the...

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Source

Identifiers

PMID: 20020158
DOI: 10.1007/s00467-009-1385-5

Genes

NPHS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Changes in glomerular mesangium in kidneys with congenital nephrotic syndrome of the Finnish type.PMID 20020158Read ↗

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