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Article

Nephrin gene (NPHS1) in patients with minimal change nephrotic syndrome (MCNS).

Kidney international - 1 May 2004

Lahdenkari Anne-Tiina, Kestilä Marjo, Holmberg Christer, Koskimies Olli, Jalanko Hannu

Abstract excerpt

BACKGROUND: Minimal change nephrotic syndrome (MCNS) is a major problem in pediatric nephrology. While the pathogenesis of MCNS is not known, the latest discoveries in the genetic diseases indicate that glomerular epithelial cells (podocytes) and the slit diaphragm play a primary role in development of proteinuria. Because nephrin is known to be a major component of the slit diaphragm, we analyzed the structure...

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Source

Identifiers

PMID: 15086927
DOI: 10.1111/j.1523-1755.2004.00583.x

Genes

NPHS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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