Article
Glomeruli from patients with nephrin mutations show increased number of ciliated and poorly differentiated podocytes.
Acta histochemica - 1 Nov 2018
Vukojevic Katarina, Raguz Fila, Saraga Marijan, Filipovic Natalija, Bocina Ivana, Kero Darko, Glavina Durdov Merica, Martinovic Vlatka, Saraga-Babic Mirna
Abstract excerpt
BACKGROUND: Podocytes are postmitotic, highly specialized cells which maintain the glomerular filtration barrier (GFB). Their injury is characterized by foot processes effacement and change in protein expression leading to proteinuria and end-stage kidney disease. METHODS: Our study focuses on the morphological and immunohistochemical changes of human podocytes during normal development and postnatal period,...
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