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Article

Melusin gene (ITGB1BP2) nucleotide variations study in hypertensive and cardiopathic patients.

BMC medical genetics - 17 Dec 2009

Palumbo Valeria, Segat Ludovica, Padovan Lara, Amoroso Antonio, Trimarco Bruno, Izzo Raffaele, Lembo Giuseppe, Regitz-Zagrosek Vera, Knoll Ralph, Brancaccio Mara, Tarone Guido, Crovella Sergio

Abstract excerpt

BACKGROUND: Melusin is a muscle specific signaling protein, required for compensatory hypertrophy response in pressure-overloaded heart. The role of Melusin in heart function has been established both by loss and gain of function experiments in murine models. With the aim of verifying the hypothesis of a potential role of the Melusin encoding gene, ITGB1BP2, in the modification of the clinical phenotype of human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20017903
DOI: 10.1186/1471-2350-10-140
PMCID: PMC2803168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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