Association of brain-derived neurotrophic factor genetic Val66Met polymorphism with severity of depression, efficacy of fluoxetine and its side effects in Chinese major depressive patients.

doi:10.1159/000265132

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Association of brain-derived neurotrophic factor genetic Val66Met polymorphism with severity of depression, efficacy of fluoxetine and its side effects in Chinese major depressive patients.

Neuropsychobiology - 1 Jan 2010

Zou Yan-Feng, Wang Yu, Liu Ping, Feng Xiao-Liang, Wang Bin-Yan, Zang Tong-Hua, Yu Xin, Wei Jing, Liu Zhong-Chun, Liu Ying, Tao Ming, Li Hui-Chun, Li Ke-Qing, Hu Jian, Li Ming, Zhang Ke-Rang, Ye Dong-Qing, Xu Xi-Ping

Abstract excerpt

BACKGROUND: Preclinical studies have shown that brain-derived neurotrophic factor (BDNF) may be involved in antidepressant action, and the BDNF gene has been suggested to be involved in the pharmacological treatment of major depressive disorder (MDD). In this study, the relationship between BDNF Val66Met polymorphism (Single Nucleotide Polymorphism Database ID: rs6265) and severity of depression, efficacy of...

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PMID: 20016225
DOI: 10.1159/000265132

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BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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