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Article

DMC1 functions in a Saccharomyces cerevisiae meiotic pathway that is largely independent of the RAD51 pathway.

Genetics - 1 Oct 1997

Dresser M E, Ewing D J, Conrad M N, Dominguez A M, Barstead R, Jiang H, Kodadek T

Abstract excerpt

Meiotic recombination in the yeast Saccharomyces cerevisiae requires two similar recA-like proteins, Dmc1p and Rad51p. A screen for dominant meiotic mutants provided DMC1-G126D, a dominant allele mutated in the conserved ATP-binding site (specifically, the A-loop motif) that confers a null phenot...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 9335591
DOI: 10.1093/genetics/147.2.533
PMCID: PMC1208176

Genes

DMC1
RAD51

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9335591-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

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DMC1 functions in a Saccharomyces cerevisiae meiotic pathway that is largely independent of the RAD51 pathway.PMID 9335591Read ↗

Saccharomyces cerevisiae recA homologues RAD51 and DMC1 have both distinct and overlapping roles in meiotic recombination.Semantic proximity Read ↗

A dominant, recombination-defective allele of Dmc1 causing male-specific sterility.Semantic proximity Read ↗

Mnd1/Hop2 facilitates Dmc1-dependent interhomolog crossover formation in meiosis of budding yeast.Semantic proximity Read ↗

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Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impaired.Semantic proximity Read ↗

Saccharomyces cerevisiae checkpoint genes MEC1, RAD17 and RAD24 are required for normal meiotic recombination partner choice.Semantic proximity Read ↗

From meiosis to postmeiotic events: Uncovering the molecular roles of the meiosis‐specific recombinase Dmc1Semantic proximity Read ↗

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Multiple pathways suppress non-allelic homologous recombination during meiosis in Saccharomyces cerevisiae.Semantic proximity Read ↗

Dmc1 of Schizosaccharomyces pombe plays a role in meiotic recombination.Semantic proximity Read ↗

Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathway.Semantic proximity Read ↗

Tid1/Rdh54 promotes dissociation of Dmc1 from nonrecombinogenic sites on meiotic chromatin.Semantic proximity Read ↗

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