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Targeting energy metabolism in brain cancer through calorie restriction and the ketogenic diet

1 Jan 2009

Abstract excerpt

Malignant brain tumors are a significant health problem in children and adults and are largely unmanageable. As a metabolic disorder involving the dysregulation of glycolysis and respiration (the Warburg effect), malignant brain cancer can be managed through changes in metabolic environment. In contrast to malignant brain tumors that are mostly dependent on glycolysis for energy, normal neurons and glia readily...

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PMID: 20009300
DOI: 10.4103/0973-1482.55134

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