Article

The efficacy of a ketogenic diet in preclinical models of IDH wild-type and IDH mutant glioma

2021-09-09

Abstract excerpt

<h4>ABSTRACT</h4> Infiltrative gliomas are the most common neoplasms arising in the brain, and remain largely incurable despite decades of research. A subset of these gliomas contains mutations in isocitrate dehydrogenase 1 ( IDH1 ) or, less commonly, IDH2 (together called “IDH mut ”). These mutations alter cellular biochemistry, and IDH mut gliomas are generally less aggressive than IDH wild-type (IDH wt )...

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Literature Corpus work: d8882218-366a-5a08-a831-e5919daa6396
DOI: 10.1101/2021.09.09.459672

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