Article

The ketogenic diet is not effective in preclinical models of IDH1 wild-type and IDH1 mutant glioma

2020-06-23

Abstract excerpt

<h4>ABSTRACT</h4> Infiltrative gliomas are the most common neoplasms arising in the brain, and remain largely incurable despite decades of research. A subset of these gliomas contains mutations in isocitrate dehydrogenase 1 (IDH1 mut ). This mutation disrupts cellular biochemistry, and IDH1 mut gliomas are generally less aggressive than IDH1 wild-type (IDH1 wt ) gliomas. Some preclinical studies and clinical...

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Literature Corpus work: d8ab0df9-5811-599e-8c90-b09d9de5703b
DOI: 10.1101/2020.06.23.166652

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