Article
A replication study of the association between the IL12B promoter allele CTCTAA and susceptibility to cerebral malaria in Thai population.
Malaria journal - 11 Dec 2009
Naka Izumi, Patarapotikul Jintana, Tokunaga Katsushi, Hananantachai Hathairad, Tsuchiya Naoyuki, Ohashi Jun
Abstract excerpt
BACKGROUND: Interleukin-12 (IL-12), a heterodimeric cytokine composed of p35 and p40 subunits, has been thought to play an important role in the pathogenesis of malaria. The IL-12p40 subunit is encoded by the IL12B gene. An IL12B promoter allele, CTCTAA, at rs17860508 has been reported to be asso...
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