Article
A functional polymorphism in the IL1B gene promoter, IL1B -31C>T, is not associated with cerebral malaria in Thailand.
Malaria journal - 14 Aug 2005
Ohashi Jun, Naka Izumi, Doi Akihiro, Patarapotikul Jintana, Hananantachai Hathairad, Tangpukdee Noppadon, Looareesuwan Sornchai, Tokunaga Katsushi
Abstract excerpt
BACKGROUND: IL-1beta and IL-1RA levels are higher in the serum of cerebral malaria patients than in patients with mild malaria. Recently, the level of IL1B expression was reported to be influenced by a polymorphism in the promoter of IL1, IL1B -31C>T. METHODS: To examine whether polymorphisms in...
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