Article
A microarray-based system for the simultaneous analysis of single nucleotide polymorphisms in human genes involved in the metabolism of anti-malarial drugs.
Malaria journal - 9 Dec 2009
Hodel Eva Maria, Ley Serej D, Qi Weihong, Ariey Frédéric, Genton Blaise, Beck Hans-Peter
Abstract excerpt
BACKGROUND: In order to provide a cost-effective tool to analyse pharmacogenetic markers in malaria treatment, DNA microarray technology was compared with sequencing of polymerase chain reaction (PCR) fragments to detect single nucleotide polymorphisms (SNPs) in a larger number of samples. METHOD...
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