Article
A microarray minisequencing system for pharmacogenetic profiling of antihypertensive drug response.
Pharmacogenetics - 1 Jan 2003
Liljedahl Ulrika, Karlsson Julia, Melhus Håkan, Kurland Lisa, Lindersson Marie, Kahan Thomas, Nyström Fredrik, Lind Lars, Syvänen Ann-Christine
Abstract excerpt
We aimed to develop a microarray genotyping system for multiplex analysis of a panel of single nucleotide polymorphisms (SNPs) in genes encoding proteins involved in blood pressure regulation, and to apply this system in a pilot study demonstrating its feasibility in the pharmacogenetics of hypertension. A panel of 74 SNPs in 25 genes involved in blood pressure regulation was selected from the SNP databases, and...
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