Article
Calsequestrins in skeletal and cardiac muscle from adult Danio rerio.
Journal of muscle research and cell motility - 1 Apr 2016
Furlan Sandra, Mosole Simone, Murgia Marta, Nagaraj Nagarjuna, Argenton Francesco, Volpe Pompeo, Nori Alessandra
Abstract excerpt
Calsequestrin (Casq) is a high capacity, low affinity Ca(2+)-binding protein, critical for Ca(2+)-buffering in cardiac and skeletal muscle sarcoplasmic reticulum. All vertebrates have multiple genes encoding for different Casq isoforms. Increasing interest has been focused on mammalian and human Casq genes since mutations of both cardiac (Casq2) and skeletal muscle (Casq1) isoforms cause different, and sometime...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.