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Article

Relationship between functional polymorphism in the Aurora A gene and susceptibility of hepatocellular carcinoma.

Journal of viral hepatitis - 1 Sept 2010

Akkiz H, Bayram S, Bekar A, Akgöllü E, Ozdil B

Abstract excerpt

Aurora A is considered a potential cancer susceptibility gene owing to overexpression or amplification of Aurora A gene that causes centrosome dysfunction, chromosome instability, tumourigenic transformation and checkpoint abnormalities. Functional coding region polymorphism F31I in the Aurora A gene has recently been shown to be associated with several human cancers, but its association with hepatocellular...

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Identifiers

PMID: 20002563
DOI: 10.1111/j.1365-2893.2009.01225.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Relationship between functional polymorphism in the Aurora A gene and susceptibility of hepatocellular carcinoma.PMID 20002563Read ↗

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Predictive Role of AURKA rs 1047972 Gene Polymorphism and the Risk of Development of Hepatocellular Carcinoma.Semantic proximity Read ↗

Functional Phe31Ile polymorphism in Aurora A and risk of breast carcinoma.Semantic proximity Read ↗

AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study.Semantic proximity Read ↗

A single nucleotide polymorphism in codon F31I and V57I of the AURKA gene in invasive ductal breast carcinoma in Middle East.Semantic proximity Read ↗

Genetic polymorphisms in AURKA and BRCA1 are associated with breast cancer susceptibility in a Chinese Han population.Semantic proximity Read ↗

Overexpression of Aurora Kinase B Is Correlated with Diagnosis and Poor Prognosis in Hepatocellular CarcinomaSemantic proximity Read ↗

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The N-terminal domain of the Aurora-A Phe-31 variant encodes an E3 ubiquitin ligase and mediates ubiquitination of IkappaBalpha.Semantic proximity Read ↗

Evaluation of Aurora-A gene polymorphism and esophageal cancer risk in a South Indian population.Semantic proximity Read ↗

Polymorphisms of the AURKA (STK15/Aurora Kinase) Gene and Breast Cancer Risk (United States).Semantic proximity Read ↗

The Aurora A F31I polymorphism is not a risk factor for glioblastoma.Semantic proximity Read ↗

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