Article

Single-dose Efficacy of a Next-Generation Mpox Vaccine Harnessing an Immunomodulatory Peptide

2026-08-03

Abstract excerpt

Rapidly deployable, single-dose vaccines that maintain durability under operational constraints remain an unmet need in outbreak preparedness. Live viral vectors such as Modified Vaccinia Ankara (MVA) offer strong safety profiles, yet their suboptimal immunogenicity often requires multidose regimens, reducing flexibility during emergency response. To address these limitations, we developed a modular vaccine platfo...

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Literature Corpus work: f8b77b52-0bd7-567f-9c51-64d7f6e58bb0
DOI: 10.64898/2026.07.31.742137

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Single-dose Efficacy of a Next-Generation Mpox Vaccine Harnessing an Immunomodulatory PeptideDOI 10.64898/2026.07.31.742137Read

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