Article
Serotonin transporter triallelic genotype and response to citalopram and risperidone in dementia with behavioral symptoms.
International clinical psychopharmacology - 1 Jan 2010
Dombrovski Alexandre Y, Mulsant Benoit H, Ferrell Robert E, Lotrich Francis E, Rosen Jules I, Wallace Meredith, Houck Patricia R, Mazumdar Sati, Pollock Bruce G
Abstract excerpt
The risk/benefit ratio of pharmacotherapy for behavioral symptoms of dementia is questionable: second-generation antipsychotics are poorly tolerated, and the efficacy of alternative treatments, for example, selective serotonin-reuptake inhibitors (SSRIs), is uncertain. Biomarkers of treatment response may improve this risk/benefit ratio. The length polymorphism of the serotonin transporter promoter gene...
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