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Article

Secreted frizzled-related protein disrupts PCP in eye lens fiber cells that have polarised primary cilia.

Developmental biology - 15 Feb 2010

Sugiyama Yuki, Stump Richard J W, Nguyen Anke, Wen Li, Chen Yongjuan, Wang Yanshu, Murdoch Jennifer N, Lovicu Frank J, McAvoy John W

Abstract excerpt

Planar cell polarity (PCP) signaling polarises cells along tissue axes. Although pathways involved are becoming better understood, outstanding issues include; (i) existence/identity of cues that orchestrate global polarisation in tissues, and (ii) the generality of the link between polarisation o...

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Share to Cell Polarity
Share to Cilia
Share to Epithelial Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Frizzled Receptors

Share to Glycoproteins

Share to Intracellular Signaling Peptides and Proteins

Share to Lens, Crystalline

Share to Receptors, G-Protein-Coupled

Source

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Identifiers

PMID: 19968984
DOI: 10.1016/j.ydbio.2009.11.033
PMCID: PMC2815166

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19968984-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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