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Article

Primary IgA nephropathy is more severe in TGF-beta1 high secretor patients.

Journal of nephrology - 1 Jan 2000

Brezzi Brigida, Del Prete Dorella, Lupo Antonio, Magistroni Riccardo, Gomez-Lira Macarena, Bernich Patrizia, Anglani Franca, Mezzabotta Federica, Turco Alberto, Furci Luciana, Ceol Monica, Antonucci Francesco, Abaterusso Cataldo, Bonfante Luciana, D'Angelo Angela, Albertazzi Alberto, Gambaro Giovanni

Abstract excerpt

BACKGROUND: IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide and is characterized by extremely variable clinical and morphological features and outcome. TGF-beta1 has a key role in fibrogenesis and the progression of renal damage. Its production is under genetic cont...

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PMID: 19967654

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19967654-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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