Article
Genetic variation in the transforming growth factor-beta1 gene is associated with susceptibility to IgA nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Oct 2009
Vuong Mai Tuyet, Lundberg Sigrid, Gunnarsson Iva, Wramner Lars, Seddighzadeh Maria, Hahn-Zoric Mirjana, Fernström Anders, Hanson Lars A, Do Lieu Thi, Jacobson Stefan H, Padyukov Leonid
Abstract excerpt
BACKGROUND: There is growing evidence of genetic risk for susceptibility to IgA nephropathy. Among several candidate genes related to immunological regulation in renal tissue, TGFB1 is known to be a contributor to proliferation and the development of fibrosis. METHODS: We analysed several SNPs in...
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