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Article

G protein beta3 subunit C825T polymorphism in primary IgA nephropathy.

Kidney international - 1 Jul 2004

Thibaudin Lise, Berthoux Patricia, Thibaudin Damien, Mariat Christophe, Berthoux François

Abstract excerpt

BACKGROUND: The T allele of the G protein beta3 subunit (GNB3) C825T polymorphism has been associated with increased signal transduction, increased activity of the kidney Na+/H+ exchanger, and also with late-onset essential hypertension. Hypertension is a strong independent risk factor for progre...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerulonephritis, IGA

Share to Heterotrimeric GTP-Binding Proteins

Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 15200440
DOI: 10.1111/j.1523-1755.2004.00734.x

Genes

GNB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15200440-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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G protein beta3 subunit C825T polymorphism in primary IgA nephropathy.PMID 15200440Read ↗

The 825C/T polymorphism of the G-protein subunit beta3 does not influence blood pressure and renal function in kidney transplant recipients.Semantic proximity Read ↗

Transmission of G-protein beta3 subunit C825T alleles to offspring affected with end-stage renal disease.Semantic proximity Read ↗

G-protein beta-3 subunit gene C825 T polymorphism: influence on plasma sodium and potassium concentrations in essential hypertensive patients.Semantic proximity Read ↗

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G-Protein beta(3) subunit C825T variant, nephropathy and hypertension in patients with type 2 (Non-insulin-dependent) diabetes mellitus.Semantic proximity Read ↗

The GNB3 C825T polymorphism and essential hypertension: a meta-analysis of 34 studies including 14,094 cases and 17,760 controls.Semantic proximity Read ↗

Association of G-protein β3 subunit C825T polymorphism with essential hypertension: evidence from 63 729 subjects.Semantic proximity Read ↗

The genetic variant C825T of the beta 3 subunit of G protein is associated with hypertension in a Portuguese population.Semantic proximity Read ↗

The C825T polymorphism in the human G-protein beta3 subunit gene is not associated with diabetic nephropathy in Type I diabetes mellitus.Semantic proximity Read ↗

The C825T polymorphism in the G-protein beta3 subunit gene and diabetic complications in IDDM patients.Semantic proximity Read ↗

G-protein beta(3) subunit gene (GNB3) 825T allele is associated with enhanced renal perfusion in early hypertension.Semantic proximity Read ↗

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