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Article

Glutathione S-transferase and cytochrome-P-450 polymorphism as risk factors for squamous cell carcinoma of the larynx.

American journal of surgery - 1 Dec 1996

Jahnke V, Matthias C, Fryer A, Strange R

Abstract excerpt

PURPOSE: While cigarette smoking and alcohol consumption are recognized covariates for laryngeal carcinoma, the role of genetic factors in determining individual susceptibility is unknown. We describe the influence of polymorphism in carcinogen-metabolizing enzymes on susceptibility to squamous c...

Read the complete abstract on PubMed

Topics

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Share to Carcinoma, Squamous Cell
Share to Cytochrome P-450 Enzyme System
Share to GSTM1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Glutathione Transferase

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 8988674
DOI: 10.1016/s0002-9610(96)00298-x

Genes

GSTM1
GSTM3
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8988674-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Glutathione S-transferase and cytochrome-P-450 polymorphism as risk factors for squamous cell carcinoma of the larynx.PMID 8988674Read ↗

[Initial results of glutathione-S-transferase GSTM1 and GSTT1 genotypes and genetic predisposition for laryngeal carcinoma].Semantic proximity Read ↗

Glutathione S-transferase and cytochrome P450 genotypes as risk factors for laryngeal carcinoma.Semantic proximity Read ↗

Genetic polymorphisms in cytochrome P450 genes are associated with an increased risk of squamous cell carcinoma of the larynx and hypopharynx in a Chinese population.Semantic proximity Read ↗

Larynx cancer risk in relation to glutathione S-transferase M1 and T1 genotypes and tobacco smoking.Semantic proximity Read ↗

CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell carcinoma.Semantic proximity Read ↗

GSTM1, GSTT1, and the risk of squamous cell carcinoma of the head and neck: a mini-HuGE review.Semantic proximity Read ↗

Glutathione S-transferase GSTM3 and GSTP1 genotypes and larynx cancer risk.Semantic proximity Read ↗

Polymorphisms in drug-metabolizing enzymes and risk to head and neck cancer: evidence for gene-gene and gene-environment interaction.Semantic proximity Read ↗

Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers: studies in upper aerodigestive tract cancers.Semantic proximity Read ↗

Genetic deletions of glutathione-S-transferase as a risk factor in squamous cell carcinoma of the larynx: a preliminary report.Semantic proximity Read ↗

Polymorphisms of GSTT1 and related genes in head and neck cancer risk.Semantic proximity Read ↗

CYP1A1, GSTM1 and GSTT1 polymorphisms, tobacco and alcohol status and risk of head and neck squamous cell carcinoma.Semantic proximity Read ↗

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