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Article

Differential expression of GSPT1 GGCn alleles in cancer.

Cancer genetics and cytogenetics - 1 Dec 2009

Malta-Vacas Joana, Ferreira Paula, Monteiro Carolino, Brito Miguel

Abstract excerpt

The human eukaryotic release factor 3a (eRF3a), encoded by the G1 to S phase transition 1 gene (GSPT1; alias eRF3a), is upregulated in various human cancers. GSPT1 contains a GGC(n) polymorphism in exon 1, encoding a polyglycine expansion in the N-terminal of the protein. The longer allele, GGC(1...

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Source

Identifiers

PMID: 19963113
DOI: 10.1016/j.cancergencyto.2009.08.010

Genes

GSPT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19963113-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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