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Article

GGCn polymorphism of eRF3a/GSPT1 gene and breast cancer susceptibility.

Medical oncology (Northwood, London, England) - 1 Sept 2012

Miri Mahboobe, Hemati Simin, Safari Foruzan, Tavassoli Manoochehr

Abstract excerpt

The significance of translation regulatory factors in elevating the risk of cancer has been recently recognized. Eukaryotic release factor 3a (eRF3a) is a translation termination protein that is encoded by G1 to S phase transition 1 gene (GSPT1). The eRF3a/GSPT1 exon 1 contains a trinucleotide GGC repeat coding for a polyglycine expansion in the N-terminal of the protein. In the present study, we determined the...

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Source

Identifiers

PMID: 22101789
DOI: 10.1007/s12032-011-0111-x

Genes

GSPT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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GGCn polymorphism of eRF3a/GSPT1 gene and breast cancer susceptibility.PMID 22101789Read ↗

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