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Article

VKORC1 mutations in patients with partial resistance to phenprocoumon.

British journal of haematology - 1 Mar 2010

Schmeits Peter C J, Hermans Mirjam H A, van Geest-Daalderop Johanna H H, Poodt Jeroen, de Sauvage Nolting Pernette R W, Conemans Jean M H

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Share to Amino Acid Sequence
Share to Anticoagulants
Share to Drug Resistance
Share to Mixed Function Oxygenases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19961479
DOI: 10.1111/j.1365-2141.2009.08017.x

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

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Research trail→

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VKORC1 mutations in patients with partial resistance to phenprocoumon.PMID 19961479Read ↗

A new VKORC1 allelic variant (p.Trp59Arg) in a patient with partial resistance to acenocoumarol and phenprocoumon.Semantic proximity Read ↗

A vitamin K epoxide reductase complex subunit-1 (VKORC1) mutation in a patient with vitamin K antagonist resistance.Semantic proximity Read ↗

VKORC1 pharmacogenomics summary.Semantic proximity Read ↗

Identification of VKORC1 genotype leading to resistance to tecarfarin.Semantic proximity Read ↗

VKORC1 mutations detected in patients resistant to vitamin K antagonists are not all associated with a resistant VKOR activity.Semantic proximity Read ↗

Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment.Semantic proximity Read ↗

Genetic causes of resistance to vitamin K antagonists in Polish patients: a novel p.Ile123Met mutation in VKORC1 gene.Semantic proximity Read ↗

Pharmacodynamic resistance to warfarin is associated with nucleotide substitutions in VKORC1.Semantic proximity Read ↗

Stabilization of warfarin-binding pocket of VKORC1 and VKORL1 by a peripheral region determines their different sensitivity to warfarin inhibition.Semantic proximity Read ↗

A vitamin K epoxide reductase complex subunit 1 mutation in an Irish patient with warfarin resistance.Semantic proximity Read ↗

Warfarin resistance associated with genetic polymorphism of VKORC1: linking clinical response to molecular mechanism using computational modeling.Semantic proximity Read ↗

Human VKORC1 mutations cause variable degrees of 4-hydroxycoumarin resistance and affect putative warfarin binding interfacesSemantic proximity Read ↗

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