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Article

Population differences in allele frequencies at the OLR1 locus may suggest geographic disparities in cardiovascular risk events.

Annals of human biology - 1 Apr 2010

Predazzi Irene M, Martínez-Labarga Cristina, Vecchione Lucia, Mango Ruggiero, Ciccacci Cinzia, Amati Francesca, Ottoni Claudio, Crawford Michael H, Rickards Olga, Romeo Francesco, Novelli Giuseppe

Abstract excerpt

BACKGROUND: Several studies have demonstrated a link between cardiovascular disease (CVD) susceptibility and the genetic background of populations. Endothelial activation and dysfunction induced by oxidized low-density lipoprotein (ox-LDL) is one of the key steps in the initiation of atherosclerosis. The oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1) gene is the main receptor of ox-LDL. We have...

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Source

Identifiers

PMID: 19961348
DOI: 10.3109/03014460903393857

Genes

OLR1
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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