Article
Prediction of avian influenza A binding preference to human receptor using conformational analysis of receptor bound to hemagglutinin.
BMC genomics - 3 Dec 2009
Jongkon Nipa, Mokmak Wanwimon, Chuakheaw Daungmanee, Shaw Philip J, Tongsima Sissades, Sangma Chak
Abstract excerpt
BACKGROUND: It is known that the highly pathogenic avian influenza A virus H5N1 binds strongly and with high specificity to the avian-type receptor by its hemagglutinin surface protein. This specificity is normally a barrier to viral transmission from birds to humans. However, strains may emerge...
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