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Article

High levels of human gamma-globin are expressed in adult mice carrying a transgene of the Brazilian type of hereditary persistence of fetal hemoglobin ((A)gamma -195).

Hemoglobin - 1 Jan 2009

da Cunha Anderson F, Brugnerotto Ana F, Corat Marcus A Finzi, Devlin Emily E, Gimenes Ana P, de Melo Mônica Barbosa, Passos Luiz A Corrêa, Bodine David, Saad Sara T O, Costa Fernando F

Abstract excerpt

Hereditary persistence of fetal hemoglobin (HPFH) is characterized by increased levels of Hb F during adult life. Nondeletional forms of HPFH are characterized by single base mutations in the (A)gamma and (G)gamma promoters, resulting in an increase of Hb F ranging from 3 to 20% in heterozygotes....

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Source

Identifiers

PMID: 19958189
DOI: 10.3109/03630260903344176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19958189-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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High levels of human gamma-globin are expressed in adult mice carrying a transgene of the Brazilian type of hereditary persistence of fetal hemoglobin ((A)gamma -195).PMID 19958189Read ↗

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