Article
Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes.
The Journal of biological chemistry - 5 Feb 2010
Péterfy Miklós, Harris Thurl E, Fujita Naoya, Reue Karen
Abstract excerpt
Lipin-1 is a bifunctional protein involved in lipid metabolism and adipogenesis. Lipin-1 plays a role in the biosynthesis of triacylglycerol through its phosphatidate phosphatase activity and also acts as a transcriptional co-activator of genes involved in oxidative metabolism. Lipin-1 resides in...
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