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Article

The tumor suppressor p53 transcriptionally regulates cGKI expression during neuronal maturation and is required for cGMP-dependent growth cone collapse.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Dec 2009

Tedeschi Andrea, Nguyen Tuan, Steele Sonya Ulrike, Feil Susanne, Naumann Ulrike, Feil Robert, Di Giovanni Simone

Abstract excerpt

The cGMP-dependent protein kinase type I (cGKI) has multiple functions including a role in axonal growth and pathfinding of sensory neurons, and counteracts Semaphorin 3A (Sema3A)-induced growth cone collapse. Within the nervous system, however, the transcriptional regulation of cGKI is still obs...

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Source

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Identifiers

PMID: 19955367
DOI: 10.1523/JNEUROSCI.4416-09.2009
PMCID: PMC2822954

Genes

PC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19955367-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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