Article
The role of rhodopsin glycosylation in protein folding, trafficking, and light-sensitive retinal degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Dec 2009
Tam Beatrice M, Moritz Orson L
Abstract excerpt
Several mutations in the N terminus of the G-protein-coupled receptor rhodopsin disrupt NXS/T consensus sequences for N-linked glycosylation (located at N2 and N15) and cause sector retinitis pigmentosa in which the inferior retina preferentially degenerates. Here we examined the role of rhodopsi...
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