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Article

Indian hedgehog, a neglected member of hedgehog pathway, may offer a novel avenue for colorectal cancer therapy.

Cancer biotherapy & radiopharmaceuticals - 1 Dec 2009

Fu Xiangsheng, Yang Xiatong, Zhao Luping

Abstract excerpt

Published data on hedgehog (Hh) pathway activation in colorectal cancer (CRC) are conflicting, and the effect of the Hh pathway inhibitor on the viability of colon cancer cells is controversial. This article focuses attention on the often-neglected, yet likely, critical role of Indian Hh in the course of colonic tumor progression and hypothesizes that upregulation of Indian Hh expression may offer a novel...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19954298
DOI: 10.1089/cbr.2009.0683

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