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Article

A family harboring a germ-line N-terminal C/EBPalpha mutation and development of acute myeloid leukemia with an additional somatic C-terminal C/EBPalpha mutation.

Genes, chromosomes & cancer - 1 Mar 2010

Nanri Tomoko, Uike Naokuni, Kawakita Toshiro, Iwanaga Eisaku, Mitsuya Hiroaki, Asou Norio

Abstract excerpt

C/EBPalpha plays an essential role as a transcription factor in myeloid cell differentiation. Here, we describe a Japanese family in which two individuals with acute myeloid leukemia (AML) and one healthy individual had an identical 4-base pair insertion in the N-terminal region of CEBPA (350_351...

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Source

Identifiers

PMID: 19953636
DOI: 10.1002/gcc.20734

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19953636-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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