Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hereditary acute myeloid leukemia associated with C-terminal CEBPA germline variants.

Familial cancer - 1 Jul 2023

Harrigan Amye M, Trottier Amy M

Abstract excerpt

Acute myeloid leukemia with germline CEBPA mutation is a subtype of acute myeloid leukemia that is associated with a favorable prognosis. Most of the reported cases of acute myeloid leukemia with CEBPA germline variants involve a germline variant in the N-terminus and a somatic variant in the C-terminus. There are only a few reported cases where the CEBPA germline variant has been identified in the C-terminus and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CCAAT-Enhancer-Binding Proteins
Share to Family
Share to Germ-Line Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Mutation

Share to Prognosis

Share to Recurrence

Source

Identifiers

PMID: 36879149
DOI: 10.1007/s10689-023-00329-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hereditary acute myeloid leukemia associated with C-terminal CEBPA germline variants.PMID 36879149Read ↗

Hereditary acute myeloid leukemia associated with C-terminal CEBPA germline variantsSemantic proximity Read ↗

A case of acute myeloid leukemia with unusual germline CEBPA mutation: lessons learned about mutation detection, location, and penetrance.Semantic proximity Read ↗

Familial CEBPA-mutated acute myeloid leukemiaSemantic proximity Read ↗

Disease evolution and outcomes in familial AML with germline CEBPA mutations.Semantic proximity Read ↗

Secondary leukemia in patients with germline transcription factor mutations (RUNX1, GATA2, CEBPA).Semantic proximity Read ↗

Clinical features and management of germline CEBPA-mutated carriers.Semantic proximity Read ↗

Another pedigree with familial acute myeloid leukemia and germline CEBPA mutationSemantic proximity Read ↗

Acute myeloid leukemia due to germline CEBPA mutation in a Syrian family.Semantic proximity Read ↗

Germline predisposition to myeloid neoplasms: Characteristics and management of high versus variable penetrance disorders.Semantic proximity Read ↗

Somatic CEBPA mutations are a frequent second event in families with germline CEBPA mutations and familial acute myeloid leukemia.Semantic proximity Read ↗

Clonal Evolution of Acute Myeloid Leukemia with CEBPA Double Mutations after Long-Term Remission: Case Report and a Literature ReviewSemantic proximity Read ↗

Sporadic and Familial Acute Myeloid Leukemia with CEBPA Mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.