Article
Understanding the HIV coreceptor switch from a dynamical perspective.
BMC evolutionary biology - 30 Nov 2009
Kamp Christel
Abstract excerpt
BACKGROUND: The entry of HIV into its target cells is facilitated by the prior binding to the cell surface molecule CD4 and a secondary coreceptor, mostly the chemokine receptors CCR5 or CXCR4. In early infection CCR5-using viruses (R5 viruses) are mostly dominant while a receptor switch towards...
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