Article
Identification of a functionally important loop in Salmonella typhimurium ArnT.
Biochemistry - 12 Jan 2010
Impellitteri Nicholas A, Merten Jacqueline A, Bretscher Lynn E, Klug Candice S
Abstract excerpt
ArnT confers resistance to the antibiotic polymyxin in Salmonella typhimurium and Escherichia coli through the modification of lipid A, a major component of the outer surface of gram-negative bacteria. ArnT transfers a neutral aminoarabinose moiety onto the negative phosphate groups of lipid A, r...
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