Article
Synthetic peptide model of an essential region of an aminoacyl-tRNA synthetase.
Biochemistry - 2 Oct 1990
Park S J, Miller W T, Schimmel P
Abstract excerpt
A 40 amino acid sequence of the unsolved structure of Escherichia coli alanine-tRNA synthetase is essential for tRNA binding and encodes an immunological determinant that cross-reacts with antibodies raised against a eukaryote (insect Bombyx mori) alanine enzyme. The secondary structure of this sequence is predicted to be an amphiphilic alpha-helix that includes one aspartyl and eight glutamyl side chain carboxyl...
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