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Article

Twin-arginine translocation system (tat) mutants of Salmonella are attenuated due to envelope defects, not respiratory defects.

Molecular microbiology - 1 Sept 2013

Craig Maureen, Sadik Adam Y, Golubeva Yekaterina A, Tidhar Avital, Slauch James M

Abstract excerpt

The twin-arginine translocation system (Tat) transports folded proteins across the cytoplasmic membrane and is critical to virulence in Salmonella and other pathogens. Experimental and bioinformatic data indicate that 30 proteins are exported via Tat in Salmonella Typhimurium. However, there are no data linking specific Tat substrates with virulence. We inactivated every Tat-exported protein and determined the...

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Identifiers

PMID: 23822642
DOI: 10.1111/mmi.12318
PMCID: PMC3811912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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