Article
[Genetic analysis of the fetus using maternal blood].
Gynecologie, obstetrique & fertilite - 1 Jan 2000
Costa J-M, Gautier E, Benachi A
Abstract excerpt
Circulating fetal DNA in maternal plasma and serum was first demonstrated by Lo et al. in 1997 and has become a useful tool for prenatal diagnosis less than five years later. There is more and more evidence that the trophoblastic cells act as the major source of this circulating fetal DNA. Contrary to fetal cells analysis in maternal blood which requires isolation and enrichment procedures, fetal DNA analysis is...
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