Article
[Antenatal determination of fetal RhD-blood type based on fetal DNA in plasma from the RhD-negative mother--secondary publication].
Ugeskrift for laeger - 26 Jun 2006
Clausen Frederik Banch, Krog Grethe Risum, Rieneck Klaus, Nielsen Leif Kofoed, Lundquist Rasmus, Finning Kirsten, Dickmeiss Ebbe, Hedegaard Morten, Dziegiel Morten Hanefeld
Abstract excerpt
We present a reliable test for prenatal prediction of fetal RhD type using maternal plasma from RhD-women. This test is needed for a future antenatal RH prophylaxis. A new real time PCR based assay targeting RHD exon 7 and a published assay for RHD exon 10 were used to determine the fetal RHD status in DNA extracted from plasma from 56 pregnant women in 15th-36th week of gestation. Prediction of fetal RhD type...
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