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Article

APOE and ACE polymorphisms and dementia risk in the older population over prolonged follow-up: 10 years of incidence in the MRC CFA Study.

Age and ageing - 1 Jan 2010

Keage H A D, Matthews F E, Yip A, Gao L, McCracken C, McKeith I G, Rubinsztein D C, Brayne C

Abstract excerpt

BACKGROUND: dementia risk conferred by apolipoprotein-E (APOE) and angiotensin-1-converting enzyme (ACE) polymorphisms have been reported for the MRC Cognitive Function and Ageing Study (CFAS) at 6-year follow-up. We concentrate on incident dementia risk over 10 years. METHODS: participants come from MRC CFAS, a multi-centre longitudinal population-based study of ageing in England and Wales. Three follow-up waves...

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Identifiers

PMID: 19939808
DOI: 10.1093/ageing/afp210
PMCID: PMC2794361

Genes

ACE
APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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