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Article

Ethnic differences in five intronic polymorphisms associated with arsenic metabolism within human arsenic (+3 oxidation state) methyltransferase (AS3MT) gene.

Toxicology and applied pharmacology - 1 Jan 2009

Fujihara Junko, Fujii Yoshimi, Agusa Tetsuro, Kunito Takashi, Yasuda Toshihiro, Moritani Tamami, Takeshita Haruo

Abstract excerpt

Human arsenic (+3 oxidation state) methyltransferase (AS3MT) is known to catalyze the methylation of arsenite, and intronic single-nucleotide polymorphisms (SNPs: G7395A, G12390C, T14215C, T35587C, and G35991A) in the AS3MT gene were shown to be related to inter-individual variation in the arsenic metabolism. In the present study, the genotyping for these SNPs was developed using the polymerase chain reaction and...

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PMID: 18976679
DOI: 10.1016/j.taap.2008.09.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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