Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Int7G24A variant of transforming growth factor-beta receptor type I is a risk factor for colorectal cancer in the male Spanish population: a case-control study.

BMC cancer - 20 Nov 2009

Castillejo Adela, Mata-Balaguer Trinidad, Guarinos Carla, Castillejo María-Isabel, Martínez-Cantó Ana, Barberá Víctor-Manuel, Montenegro Paola, Ochoa Enrique, Lázaro Rafael, Guillén-Ponce Carmen, Carrato Alfredo, Soto José-Luís

Abstract excerpt

BACKGROUND: The Int7G24A variant of transforming growth factor-beta receptor type I (TGFBR1) has been shown to increase the risk for kidney, ovarian, bladder, lung and breast cancers. Its role in colorectal cancer (CRC) has not been established. The aims of this study were to assess the association of TGFBR1*Int7G24A variant with CRC occurrence, patient age, gender, tumour location and stage. METHODS: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Serine-Threonine Kinases

Share to Receptor, Transforming Growth Factor-beta Type I

Share to Receptors, Transforming Growth Factor beta

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Sex Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 19930569
DOI: 10.1186/1471-2407-9-406
PMCID: PMC2784798

Genes

TGFBR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Int7G24A variant of transforming growth factor-beta receptor type I is a risk factor for colorectal cancer in the male Spanish population: a case-control study.PMID 19930569Read ↗

Int7G24A variant of transforming growth factor-beta receptor type I is associated with invasive breast cancer.Semantic proximity Read ↗

Int7G24A variant of the TGFBR1 gene and cancer risk: a meta-analysis of three case-control studies.Semantic proximity Read ↗

Association between Int7G24A rs334354 polymorphism and cancer risk: a meta-analysis of case-control studies.Semantic proximity Read ↗

An intronic variant of the TGFBR1 gene is associated with carcinomas of the kidney and bladder.Semantic proximity Read ↗

Comprehensive assessment of variation at the transforming growth factor beta type 1 receptor locus and colorectal cancer predisposition.Semantic proximity Read ↗

Transforming growth factor-β1 gene promoter -509C/T polymorphism in association with expression affects colorectal cancer development and depends on gender.Semantic proximity Read ↗

The association of polymorphisms on TGFBR1 and colorectal cancer risk: a meta-analysis.Semantic proximity Read ↗

TGFBR1 intralocus epistatic interaction as a risk factor for colorectal cancer.Semantic proximity Read ↗

Int7G24A variant of transforming growth factor-beta receptor 1 is associated with osteosarcoma susceptibility in a Chinese population.Semantic proximity Read ↗

TGFBR1*6A polymorphism in sporadic and familial colorectal Carcinoma: a case-control study and systematic literature review.Semantic proximity Read ↗

Genetic variations in the TGFβ signaling pathway, smoking and risk of colorectal cancer in a Chinese population.Semantic proximity Read ↗

Multiple genetic variants are associated with colorectal cancer risk in the Han Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.