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Article

Int7G24A variant of transforming growth factor-beta receptor 1 is associated with osteosarcoma susceptibility in a Chinese population.

Medical oncology (Northwood, London, England) - 1 Jun 2011

Hu Yun-Sheng, Pan Yong, Li Wen-Hai, Zhang Yong, Li Jun, Ma Bao-An

Abstract excerpt

The TGF-beta signaling pathway is important in the development and invasion of cancers. Int7G24A is an intronic variant of TGF-beta receptor type 1 and has been shown to be associated with the occurrence of some kinds of cancers. Nevertheless, the association of this polymorphism with osteosarcoma is unknown. In this study, we evaluated Int7G24A variant frequencies in osteosarcoma cases. The case-control study...

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Source

Identifiers

PMID: 20354825
DOI: 10.1007/s12032-010-9483-6

Genes

TGFBR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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