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Article

An intronic variant of the TGFBR1 gene is associated with carcinomas of the kidney and bladder.

International journal of cancer - 10 Nov 2004

Chen Taiping, Jackson Chad, Costello Ben, Singer Natalie, Colligan Bruce, Douglass Larry, Pemberton Jackson, Deddens James, Graff Jeremy R, Carter Julia H

Abstract excerpt

TGF-beta signaling is frequently perturbed in many human cancers, including renal cell carcinomas (RCCs) and transitional cell carcinomas (TCCs) of the bladder. Genetic alterations of the TGF-beta type 1 receptor (TGFBR1) may contribute to these perturbations. We therefore examined variations in the TGFBR1 gene by PCR, SSCP and RFLP in carcinomas of the urinary system and in tissues from noncancer, age-matched...

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Share to Activin Receptors, Type I
Share to Carcinoma, Renal Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Transforming Growth Factor-beta Type I

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Source

Identifiers

PMID: 15382067
DOI: 10.1002/ijc.20419

Genes

TGFBR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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