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Article

The death effector domains of caspase-8 induce terminal differentiation.

PloS one - 18 Nov 2009

Mielgo Ainhoa, Torres Vicente A, Schmid Michael C, Graf Ryon, Zeitlin Samantha G, Lee Pedro, Shields David J, Barbero Simone, Jamora Colin, Stupack Dwayne G

Abstract excerpt

The differentiation and senescence programs of metazoans play key roles in regulating normal development and preventing aberrant cell proliferation, such as cancer. These programs are intimately associated with both the mitotic and apoptotic pathways. Caspase-8 is an apical apoptotic initiator th...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19924290
DOI: 10.1371/journal.pone.0007879
PMCID: PMC2774162

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19924290-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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