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Article

Human death effector domain-associated factor interacts with the viral apoptosis agonist Apoptin and exerts tumor-preferential cell killing.

Cell death and differentiation - 1 May 2004

Danen-van Oorschot A A A M, Voskamp P, Seelen M C M J, van Miltenburg M H A M, Bolk M W, Tait S W, Boesen-de Cock J G R, Rohn J L, Borst J, Noteborn M H M

Abstract excerpt

Apoptin, a protein from chicken anemia virus without an apparent cellular homologue, can induce apoptosis in mammalian cells. Its cytotoxicity is limited to transformed or tumor cells, making Apoptin a highly interesting candidate for cancer therapy. To elucidate Apoptin's mechanism of action, we...

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PMID: 14765135
DOI: 10.1038/sj.cdd.4401391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14765135-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Human death effector domain-associated factor interacts with the viral apoptosis agonist Apoptin and exerts tumor-preferential cell killing.PMID 14765135Read ↗

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